Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19

To the Editor: A recent article suggested the rapid decay of anti–SARS-CoV-2 IgG in early infection, 1 but the rate was not described in detail. We evaluated persons who had recovered from Covid-19 and referred themselves to our institution […]

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Longitudinal dynamics of the neutralizing antibody response to SARS-CoV-2 infection

Abstract Background Coronavirus disease 2019 (COVID-19) is a global pandemic with no licensed vaccine or specific antiviral agents for therapy. Little is known about the longitudinal dynamics of SARS-CoV-2-specific neutralizing antibodies (NAbs) in COVID-19 patients. Methods Blood samples (n=173) […]

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How seroprevalence is helping us in the fight against COVID-19

Coloured transmission electron micrograph (TEM) of a SARS-CoV-2 coronavirus particle isolated from a UK case of the disease Covid-19. PHE’s Head of immunisation Dr Mary Ramsay describes how testing blood samples is helping us gather crucial data on the […]

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Chinese study: Antibodies in COVID-19 patients fade quickly

A new study from China showed that antibodies faded quickly in both asymptomatic and symptomatic COVID-19 patients during convalescence, raising questions about whether the illness leads to any lasting immunity to the virus afterward. The study, which focused on […]

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Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients.

COVID-19 is an ongoing global crisis in which the development of effective vaccines and therapeutics will depend critically on understanding the natural immunity to the virus, including the role of SARS-CoV-2-specific T cells. We have conducted a study of […]

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Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge

In December 2019 an outbreak of coronavirus disease (COVID-19) emerged in Wuhan, China. The causative agent was subsequently identified and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which rapidly spread worldwide causing a pandemic. Currently there are no […]

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Coronavirus: Study suggests COVID-19 immunity could last just six months

There is limited research on how long coronavirus antibodies last A person could be re-infected with coronavirus in six months, new research suggests, in a blow to the push for “immunity passports” as evidence of recovery from the illness. […]

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