How a British team discovered the first life-saving coronavirus drug

In mid-June a British research team announced that a cheap, safe, widely available drug called dexamethasone makes a huge difference in saving the lives of people severely ill with Covid-19. Perhaps no one was more surprised than the people […]

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Pixatimod (PG545), a clinical-stage heparan sulfate mimetic, is a potent inhibitor of the SARS-CoV-2 virus

A major global effort is currently ongoing to search for therapeutics and vaccines to treat or prevent infection by the SARS-CoV-2 virus. Repurposing existing entities is one attractive approach. The heparan sulfate mimetic pixatimod is a clinical-stage synthetic sulfated […]

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This Coronavirus Doesn’t Change Quickly, And That’s Good News For Vaccine Makers

Internationally, scientists now have on file the genomes of more than 47,000 different samples of the virus that causes COVID-19 — up from just one in January. Here’s a transmission electron micrograph of SARS-CoV-2 virus particles (orange) isolated from […]

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Vaccines for COVID-19: the current state of play

Introduction: COVID-19 is the disease caused by a novel betacoronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). The disease was first reported in December 2019 Wuhan, China [1] and the full genome was sequenced and published by January […]

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COVIDep: a web-based platform for real-time reporting of vaccine target recommendations for SARS-CoV-2

In response to this challenge, we have developed COVIDep (), a first-of-its-kind web-based platform that pools genetic data for SARS-CoV-2 and immunological data for the 2003 SARS virus, SARS-CoV, to identify B-cell and T-cell epitopes to serve as vaccine […]

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Covid-19 news: Dexamethasone drug saves lives of coronavirus patients

Dexamethasone is the first drug anywhere in the world that’s been found to reduce mortality from covid-19. Felipe Caparros Cruz / Alamy Latest coronavirus news as of 5 pm on 16 June First drug found to save lives in […]

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Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients.

COVID-19 is an ongoing global crisis in which the development of effective vaccines and therapeutics will depend critically on understanding the natural immunity to the virus, including the role of SARS-CoV-2-specific T cells. We have conducted a study of […]

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