U.S. Will Pay $1.6 Billion to Novavax for Coronavirus Vaccine

Andrew Caballero-Reynolds/Agence France-Presse — Getty Images The federal government will pay the vaccine maker Novavax $1.6 billion to expedite the development of 100 million doses of a coronavirus vaccine by the beginning of next year, the company said on […]

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The Importance of Advancing SARS-CoV-2 Vaccines in Children

Abstract While the role of children in the chain of transmission of SARS-CoV-2 remains to be fully defined, they likely play an important role based on our knowledge of other respiratory viruses. Children are more likely to be asymptomatic […]

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Operation Warp Speed’s opaque choices of COVID-19 vaccines draw Senate scrutiny

During a hearing on COVID-19 vaccines, Francis Collins, director of the National Institutes of Health, showed off a replica of the virus that causes the disease. Science’s COVID-19 reporting is supported by the Pulitzer Center. The leaders of Operation […]

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Experimental COVID-19 Vaccine Shows Positive Early Results in Human Trial

BioNTech of Germany and the US pharmaceutical giant Pfizer reported positive preliminary results on Wednesday from a joint project to develop a coronavirus vaccine. Known as BNT162b1, it produces antibody responses at or above the levels seen in any […]

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This Coronavirus Doesn’t Change Quickly, And That’s Good News For Vaccine Makers

Internationally, scientists now have on file the genomes of more than 47,000 different samples of the virus that causes COVID-19 — up from just one in January. Here’s a transmission electron micrograph of SARS-CoV-2 virus particles (orange) isolated from […]

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Vaccines for COVID-19: the current state of play

Introduction: COVID-19 is the disease caused by a novel betacoronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). The disease was first reported in December 2019 Wuhan, China [1] and the full genome was sequenced and published by January […]

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COVIDep: a web-based platform for real-time reporting of vaccine target recommendations for SARS-CoV-2

In response to this challenge, we have developed COVIDep (), a first-of-its-kind web-based platform that pools genetic data for SARS-CoV-2 and immunological data for the 2003 SARS virus, SARS-CoV, to identify B-cell and T-cell epitopes to serve as vaccine […]

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Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients.

COVID-19 is an ongoing global crisis in which the development of effective vaccines and therapeutics will depend critically on understanding the natural immunity to the virus, including the role of SARS-CoV-2-specific T cells. We have conducted a study of […]

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