Phase 3 trial for Moderna COVID-19 vaccine begins amid US summer surge

Today marks the start of the phase 3 trial of Moderna’s COVID-19 vaccine candidate. The COVE trial (Coronavirus Efficacy) will enroll 30,000 people at 89 sites across the country, with half the recipients receiving two shots of the vaccine […]

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Late-stage coronavirus vaccine trial starts today in the US

The first large phase 3 trial of a candidate coronavirus vaccine in the U.S. began today (July 27). The biotech company Moderna is conducting the phase 3 trial, called COVE (Coronavirus Efficacy), in collaboration with the National Institute of […]

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Development of a Multi-Antigenic SARS-CoV-2 Vaccine Using a Synthetic Poxvirus Platform

Abstract Modified Vaccinia Ankara (MVA) is a highly attenuated poxvirus vector that is widely used to develop vaccines for infectious diseases and cancer. We developed a novel vaccine platform based on a unique three-plasmid system to efficiently generate recombinant […]

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The First Coronavirus Vaccine Tested in Humans Shows Early Promise

Ted S. Warren/Associated Press An experimental coronavirus vaccine made by the biotech company Moderna provoked a promising immune response against the virus and appeared safe in the first 45 people who received it, researchers reported on Tuesday in The […]

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U.S. Will Pay $1.6 Billion to Novavax for Coronavirus Vaccine

Andrew Caballero-Reynolds/Agence France-Presse — Getty Images The federal government will pay the vaccine maker Novavax $1.6 billion to expedite the development of 100 million doses of a coronavirus vaccine by the beginning of next year, the company said on […]

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