COVID-19 in a Patient With HIV Infection

Abstract The worldwide pandemic of the novel coronavirus disease 2019 (COVID-19) has raised many challenges and uncertainties regarding disease management and prognosis in immunocompromised patient populations. The concurrence of human immunodeficiency virus (HIV) infection with severe acute respiratory syndrome […]

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Polio, measles, other diseases set to surge as COVID-19 forces suspension of vaccination campaigns

Door-to-door campaigns against polio, such as this one in Kenya in 2018, could help spread COVID-19. Science’s COVID-19 reporting is supported by the Pulitzer Center. “A devil’s choice.” That’s how Seth Berkley, head of GAVI, the Vaccine Alliance, describes the dilemma facing global health organizations in the past few […]

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Articles Comparison of shortened mosaic HIV-1 vaccine schedules: a randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) and a preclinical study in rhesus monkeys (NHP 17–22)

Summary Current efficacy studies of a mosaic HIV-1 prophylactic vaccine require four vaccination visits over one year, which is a complex regimen that could prove challenging for vaccine delivery at the community level, both for recipients and clinics. In this study, we evaluated the safety, tolerability, and immunogenicity of […]

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Gladstone scientists identify new human genes controlling HIV infection

IMAGE: Gladstone Staff Scientist David Gordon and Senior Investigator Nevan Krogan have developed a new approach to uncover human genes that control HIV infection. view more Credit: Lauren Bayless, Gladstone Institutes SAN FRANCISCO, CA February 20, 2020–Viruses are parasites. The only way they can grow is by hijacking their […]

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Atomic structures mapped in measles, mumps, flu and RSV

The atomic structure of a polymerase in human parainfluenza virus 5 reveals an irregular, round-shaped globule with a long tail made of four phosphoproteins. The structure contains more than 2,000 amino acids and five proteins. Credit: Northwestern University Northwestern University researchers have, for the first time, determined the 3-D […]

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FDA Approves Vaccine Against Possible H5N1 Influenza Pandemic in the US

Right now, on one side, the world is looking for a way to deal with coronavirus pandemic, on the other side, the government of the United States has been making efforts to protect people against a possible H5N1 influenza pandemic . Last Friday, January 30, 2020, Seqirus’ Audenz got […]

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Structure of key pneumonia virus enzyme uncovered

Scientists have used cryo-electron microscopy to clarify the structure of one of the key components of RSV and HMPV, which could lead to new therapies for the viruses. Scientists have found a potential new route to disabling respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) after elucidating the structure […]

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