Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial – The Lancet

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One U.K. trial is transforming COVID-19 treatment. Why haven’t others delivered more results?

A World Health Organization–led global trial of treatments for COVID-19 was slow to enroll coronavirus-infected people, like this one in a Spanish intensive care unit, whereas a large trial in the United Kingdom quickly produced results for three treatments. […]

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How a British team discovered the first life-saving coronavirus drug

In mid-June a British research team announced that a cheap, safe, widely available drug called dexamethasone makes a huge difference in saving the lives of people severely ill with Covid-19. Perhaps no one was more surprised than the people […]

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Coronavirus Live Updates: As Officials Fight Vaccine Skepticism, Fauci Warns U.S. Could Hit 100,000 Daily Cases

Fauci warns that the U.S. could see 100,000 new cases a day, and officials aim to counter vaccine skeptics. Dr. Anthony S. Fauci, the nation’s top infectious disease expert, warned Tuesday that the number of new infections in the […]

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Pixatimod (PG545), a clinical-stage heparan sulfate mimetic, is a potent inhibitor of the SARS-CoV-2 virus

A major global effort is currently ongoing to search for therapeutics and vaccines to treat or prevent infection by the SARS-CoV-2 virus. Repurposing existing entities is one attractive approach. The heparan sulfate mimetic pixatimod is a clinical-stage synthetic sulfated […]

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Global Coronavirus Death Toll Nears 500,000

Dr. Anthony Fauci, right, director of the National Institute of Allergy and Infectious Diseases, listens as Vice President Pence speaks during a news conference with the Coronavirus Task Force at the Department of Health and Human Services on Friday. […]

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