Study: Baloxavir prevents spread of flu to household members

The antiviral drug baloxavir (Xofluza) prevented influenza in household contacts of infected patients, according to a study yesterday in the New England Journal of Medicine , but a US expert outlined several caveats about the findings. The multicenter randomized […]

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Emerging flu virus in Chinese pigs has pandemic potential, researchers say

A multi-year study of flu viruses in pigs across 10 China provinces identified a swine influenza strain with the potential for pandemic spread in humans, researchers from China reported yesterday, based on experiments that also found that swine workers […]

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The True Coronavirus Case Tally in The US Could Be Over 80 Times Larger Than Reported

Crowded New York subway platform on May 30. (Alexi Rosenfeld/Getty Images) The US may never know the true tally of its coronavirus infections – but scientists are getting closer to an accurate count. New research suggests that many millions […]

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Are Co-Infections With COVID-19 and Influenza Low or Underreported? An Observational Study Examining Current Published Literature Including Three New Unpublished Cases

Abstract As the COVID-19 pandemic continues, one major point of uncertainty is the impact this novel pathogen will have during the upcoming 2020-2021 flu season. While the influenza virus is a known contributor to human morbidity and mortality, the […]

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The Epidemiology and Clinical Characteristics of Co-Infection of SARS-CoV-2 and Influenza Viruses in Patients During COVID-19 Outbreak

Abstract In this study, we performed a single-centred study of 307 SARS-CoV-2 infected patients. It was found that co-infection of SARS-CoV-2 and influenza virus was common during COVID-19 outbreak. And patients co-infected with SARS-CoV-2 and influenza B virus have […]

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Global between-countries variance in SARS-CoV-2 mortality is driven by reported prevalence, age distribution, and case detection rate

Objective: To explain the global between-countries variance in number of deaths per million citizens (nDpm) and case fatality rate (CFR) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Design: Systematic analysis. Data sources: Worldometer, European Centre for […]

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A Comparison of Clinical and Chest CT Findings in Patients With Influenza A (H1N1) Virus Infection and Coronavirus Disease (COVID-19)

Abstract OBJECTIVE. The purpose of this study was to compare clinical and chest CT findings in patients with influenza A (H1N1) pneumonia and coronavirus disease (COVID-19) pneumonia. MATERIALS AND METHODS. Thirty patients with diagnosed influenza A (H1N1) virus infection […]

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The p150 Isoform of ADAR1 Blocks Sustained RLR signaling and Apoptosis during Influenza Virus Infection

Signaling through retinoic acid inducible gene I (RIG-I) like receptors (RLRs) is tightly regulated, with activation occurring upon sensing of viral nucleic acids, and suppression mediated by negative regulators. Under homeostatic conditions aberrant activation of melanoma differentiation-associated protein-5 (MDA5) […]

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