Understanding the role of antibody glycosylation through the lens of severe viral and bacterial diseases.


Abstract Abundant evidence points to a critical role for antibodies in protection and pathology across infectious diseases. While the antibody variable domain facilitates antibody binding and the blockade of infection, the constant domain (Fc) mediates cross-talk with the innate immune system. The biological activity of the Fc region is […]

Click here to view original web page at www.ncbi.nlm.nih.gov